Public Events Archives

March 20, 2021

FDIME Research Grant Award 2019 ECIM 2021 (March 19, 2021)

During the virtual ECIM 2021 the recipient of the FDIME Research Grant 2019 has presented his achievements. After a short introduction on the aims and activities of FDIME Daniel Sereni, (FDIME President) announced the 2019 winner Francois Rodrigues, resident internal medicine in Paris, who wanted to spend time in Leeds at the Institute of Rheumatic and Musculoskeletal Research to build a collaboration between two institutes. The period of investigations was intended to be from January up to October 2020. The research is about a rare familial inflammatory disease. The aim of the project is to better understand the way inflammatory cells are stimulated ; this could lead to the finding of therapeutic targets. Below you can read more details for doctors and scientists and of course also for other interested readers. The initial project was on courier transfer of blood samples of patients with TNF receptor associated periodic syndrome (TRAPS). He learned several laboratory techniques, but before the first patient arrived both laboratories in Paris and Leeds were close because of Covid 19. He resumed his work in September 2020 with a new project: Multiple cell isolation (neutrophils, B cells, T cells, monocytes) from whole blood of patients with UBA1 […]

March 21, 2021

FDIME Best Research Abstracts Awards ECIM 2021 (March 20, 2021)

During the virtual ECIM 2021 three abstracts were awarded as FDIME best research abstracts. A jury consisting of Jan Willem Elte (FDIME Secretary General), Ramon Pujol (FDIME Vice President), Nicola Montana (Past EFIM President and FDIME Board member) and Runolfur Palsson (Past-past EFIM President and FDIME Board member) made the definitive selection. The following three abstracts received the awards: 76 IMPAIRED HOST ANTIVIRAL TH1 AND CD8 RESPONSE IN HIGHLY INFLAMMATORY SARS-COV-2 PATIENTS Dr Janine Rupp from Austria The T cell composition, activation and proliferation in patients with severe (n=8) or critical (n=12) Covid 19 and matched healthy controls ( 2 per Covid patient) were assessed. Beside lymphopenia several abnormal Th cell patterns were identified and also CD4+ and CD8+ cells amongst others differed from healthy controls suggesting active anti-viral T cell defense. Conclusion: the data suggest that SARS-CoV-2 induced CRS ( cytokine release syndrome) may impair viral clearance by blunting the antiviral T-cell response. 115 EFFICACY OF CDSS IN IMPROVING ANTI-RESORPTIVE BONE PROTECTIVE THERAPY AMONGST ORTHOGERIATRIC INPATIENTS: A COMPARISON STUDY Dr Lata Bhandary from Ireland Subject of the study was to compare the proportion of patients commenced on ABPT ( anti-resorptive bone protective therapy) following the introduction of a clinical […]

May 18, 2021

Benefit Concerts

Benefit Concerts with classical music have been held since 2010 to help generate funds for Research in the study of Rare Diseases:- Geneva Victoria Hall 4 March 2016 Zurich Tonhalle 21 October 2013 Paris Salle Pleyel 22 October 2010 Comments from Prof Daniel Sereni, FDIME President:- We have had excellent attendances at our Benefit classical music concerts in recent years. Audiences came from far and wide to support the events. I would like to thank not only the musicians for providing us with truly memorable and highly enjoyable evenings, but I would also like to express my gratitude to all the members of the audience who came to share these events. Your support is enormously appreciated, and has contributed to highly successful fund raising events for FDIME. The revenue from ticket sales is used specifically for research and study of Rare Diseases in Internal Medicine. We expect to arrange another Benefit Concert in 2018 or 2019.

October 7, 2021

Abstracts FDIME Grant winners

Moulis (France, 2017): The prevalence of thrombocytopenia (too few platelets) and thrombocytosis (too many platelets) and the association with hospital admission and mortality. Platelets are involved in clot formation. However, they have multiple effects. Notably, they are involved in immune system regulation, participating in the control of infections, and may complicate auto-immune diseases and cancers. Abnormal platelet count (thrombocytopenia and thrombocytosis) reflect disease severity in many condition and therefore can be used as a biomarker of disease severity in patients acutely admitted to hospital for medical conditions. Arvaniti (Greece, 2018): Epigenetics (changes in genes expression) in autoimmune liver diseases (ALDs) In our research we studied complex chemical processes and genetic (DNA) changes in blood cells (B and T lymphocytes) in patients with autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC). A relationship between changes in these chemical processes with disease activity was found, probably explaining part of the pathogenesis of the diseases and opening new ways for treatment strategies. Lanzillotta (Italy, 2020): Towards treatment optimization in autoimmune pancreatitis (AIP). Autoimmune pancreatitis (AIP) is a rare form of inflammation of the pancreas. It carries a higher risk for metabolic and infectious complications, related to glycaemic derangements and biliary strictures or immunosuppressive […]